Samuel D. Rabkin,
Samuel D. Rabkin is the Thomas A. Pappas Professor in Neurosciences and Professor of Neurosurgery (Microbiology & Immunobiology) at Harvard Medical School, Boston MA, and Virologist in Neurosurgery at Massachusetts General Hospital, Boston, MA. He is Co-Director of the Brain Tumor Research Center at Massachusetts General Hospital and an affiliated member of the Harvard Stem Cell Institute and Dana-Farber/Harvard Cancer Center. He serves on the Editorial Board of Molecular Therapy and is an Associate Editor of Molecular Therapy-Oncolytics. After obtaining his PhD at the University of Chicago, he was an Assistant Member in Molecular Biology at Memorial Sloan-Kettering Cancer Center, New York, NY, and an Associate Professor in Neurosurgery at Georgetown University Medical Center, Washington DC. Dr. Rabkin's research has focused on the development of herpes simplex virus (HSV) vectors for gene therapy in the nervous system and as oncolytic viruses for cancer therapy. Our laboratory has been studying all aspects of oncolytic HSV vectors, from construction of new vectors, novel combination strategies, and immunotherapy, to clinical translation for malignant brain tumors. We are also interested in understanding and targeting cancer stem cells in tumors of the nervous system, including glioblastoma and malignant peripheral nerve sheath tumors arising in neurofibromatosis type 1.