Faculty
Michael Absoud
Children’s Neurosciences Centre
UK
Dr. Michael Absoud was appointed as consultant in children’s neurodisability at Evelina London Children’s Hospital in 2012. He is an honorary research fellow at King’ College London. His PhD clinical research fellowship training (health and population sciences) was at the University of Birmingham. He has a major interest in childhood complex neurodevelopmental disorders and co-morbidities in neurogenetic and acquired neurological diseases, where he holds multiple grants involving national and international collaborations.
Karel Allegaert
NICU Leuven
Belgium
Prof dr Karel Allegaert, MD, PhD
Pediatrician, neonatologist
Clinical pharmacologist
Research fields:
Perinatal pharmacology
Pediatric pain
Clinical pharmacology (newborn, infant)
Current positions:
Consultant, NICU Leuven, Belgium
Professor, KU Leuven, Belgium
Council member ESPR, ESDPP
Scientific output:
About 240 PubMed citations and 10 chapters of textbooks, mainly related to perinatal pharmacology, pediatric pain and topics on clinical neonatology.
Jordi Anton
Hospital Sant Joan de Déu
Spain
Prof. Jordi Anton, MD, Phd
Abridged Curriculum Vitae
Full Name: Jordi Antón
Date of Birth: 3rd august 1968
Nationality: Spanish
Academic Title: Pediatrician, MD, PhD
Present Position (including name and address of the institution):
Senior Attendant. Pediatric Rheumatology Unit. Pediatrics Department.
Hospital Sant Joan de Deu
University of Barcelona.
Paaseig Sant Joan de Deu, 2. 08950 Esplugues (Barcelona)
Starting Date in this Position: September 2003
Relevant Professional Qualifications (Post Graduate Training):
Qualification Dates
Pediatrics 1994-1997
Pediatric rheumatology 1999-2000
Associate professor. University of Barcelona 2005-
Relevant Experience / Positions (Responsibility/Years):
Experience Dates
Pediatrics Departament. Hospital of Sabadell. Corporaciò Parc Taulí 1998-2003
President. Spanish Pediatric Rheumatology Society (SERPE) 2011-
Other relevant information (e.g. Publications, participation in International Conferences/Clinical Trials):
Dates
1: Minoia F, Davì S, Horne A, Demirkaya E, Bovis F, Li C, Lehmberg K, Weitzman S, Insalaco A, Wouters C, Shenoi S, Espada G, Ozen S, Anton J, Khubchandani R, Russo R, Pal P, Kasapcopur O, Miettunen P, Maritsi D, Merino R, Shakoory B, Alessio M, Chasnyk V, Sanner H, Gao Y, Huasong Z, Kitoh T, Avcin T, Fischbach M, Frosch M, Grom A, Huber A, Jelusic M, Sawhney S, Uziel Y, Ruperto N, Martini A, Cron RQ, Ravelli A; on behalf of the Pediatric Rheumatology International Trials Organization; the Childhood Arthritis & Rheumatology Research Alliance; the Pediatric Rheumatology Collaborative Study Group, and the Histiocyte Society. Clinical features, treatment and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis A multinational, multicenter study of 362 patients. Arthritis Rheumatol. 2014 Jul 30. doi: 10.1002/art.38802.
[Epub ahead of print]
2: Giménez-Roca C, Iglesias E, Torrente-Segarra V, Bou R, Sánchez-Manubens J, Calzada-Hernández J, Hernández S, Ricart S, Antón J. Efficacy and safety of TNF-alpha antagonists in children with juvenile idiopathic arthritis who started treatment under 4 years of age. Rheumatol Int. 2014 Aug 3. [Epub ahead of print]
3: Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V, Barberà-Cremades M, Yagüe J, Ruiz-Ortiz E, Antón J, Buján S, Couillin I, Brough D, Arostegui JI, Pelegrín P. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat Immunol. 2014 Aug;15(8):738-48.
4: Bou R, Iglesias E, Antón J. Treatment of uveitis associated with juvenile
idiopathic arthritis. Curr Rheumatol Rep. 2014 Aug;16(8):437.
5: Hofer M, Pillet P, Cochard MM, Berg S, Krol P, Kone-Paut I, Rigante D, Hentgen V, Anton J, Brik R, Neven B, Touitou I, Kaiser D, Duquesne A, Wouters C, Gattorno M. International periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome cohort: description of distinct phenotypes in 301 patients. Rheumatology (Oxford). 2014 Jun;53(6):1125-9.
6: García-De-Vicuña C, Díaz-Llopis M, Salom D, Bou R, Díaz-Cascajosa J,
Cordero-Coma M, Ortega G, Ortego-Centeno N, Suarez-De-Figueroa M, Cruz-Martínez J, Fonollosa A, Blanco R, García-Aparicio ÁM, Benítez-Del-Castillo JM, Antón J. Usefulness of adalimumab in the treatment of refractory uveitis associated with juvenile idiopathic arthritis. Mediators Inflamm. 2013;2013:560632.
7: Sánchez-Manubens J, Bou R, Anton J. Diagnosis and classification of Kawasaki disease. J Autoimmun. 2014 Feb-Mar;48-49:113-7.
8. Nakagawa K, Gonzalez-Roca E, Souto A, Kawai T, Umebayashi H, Campistol JM, Cañellas J, Takei S, Kobayashi N, Callejas-Rubio JL, Ortego-Centeno N, Ruiz-Ortiz E, Rius F, Anton J, Iglesias E, Jimenez-Treviño S, Vargas C, Fernandez-Martin J, Calvo I, Hernández-Rodríguez J, Mendez M, Dordal MT, Basagaña M, Bujan S, Yashiro M, Kubota T, Koike R, Akuta N, Shimoyama K, Iwata N, Saito MK, Ohara O, Kambe N, Yasumi T, Izawa K, Kawai T, Heike T, Yagüe J, Nishikomori R, Aróstegui JI. Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by
different phenotypes of cryopyrin-associated periodic syndromes. Ann Rheum Dis. 2013 Dec 10. [Epub ahead of print]
9. Iglesias E, Torrente-Segarra V, Bou R, Ricart S, González MI, Sánchez J,
Calzada J, Antón J. Non-systemic juvenile idiopathic arthritis outcome after
reaching clinical remission with anti-TNF-α therapy: a clinical practice
observational study of patients who discontinued treatment. Rheumatol Int. 2013 Oct 26. [Epub ahead of print]
10: Pelegrín L, Casaroli-Marano R, Antón J, Carmen García de Vicuña M, Molina-Prat N, Ignacio Aróstegui J, Yagüe J, Ríos J, Adán A. Predictive Value of Selected Biomarkers, Polymorphisms, and Clinical Features for Oligoarticular Juvenile Idiopathic Arthritis-associated Uveitis. Ocul Immunol Inflamm. 2013 Oct 16. [Epub ahead of print].
11: Burns JC, Herzog L, Fabri O, Tremoulet AH, Rodó X, Uehara R, Burgner D, Bainto E, Pierce D, Tyree M, Cayan D; Kawasaki Disease Global Climate Consortium. Seasonality of Kawasaki disease: a global perspective. PLoS One. 2013 Sep 18;8(9):e74529.
12: Lachmann HJ, Papa R, Gerhold K, Obici L, Touitou I, Cantarini L, Frenkel J, Anton J, Kone-Paut I, Cattalini M, Bader-Meunier B, Insalaco A, Hentgen V, Merino R, Modesto C, Toplak N, Berendes R, Ozen S, Cimaz R, Jansson A, Brogan PA, Hawkins PN, Ruperto N, Martini A, Woo P, Gattorno M; for the Paediatric Rheumatology International Trials Organisation (PRINTO), the EUROTRAPS and the Eurofever Project. The phenotype of TNF receptor-associated autoinflammatory syndrome (TRAPS) at presentation: a series of 158 cases from the Eurofever/EUROTRAPS international registry. Ann Rheum Dis. 2013 Aug 21. [Epub ahead of print]
13: Bishop N, Adami S, Ahmed SF, Antón J, Arundel P, Burren CP, Devogelaer JP, Hangartner T, Hosszú E, Lane JM, Lorenc R, Mäkitie O, Munns CF, Paredes A, Pavlov H, Plotkin H, Raggio CL, Reyes ML, Schoenau E, Semler O, Sillence DO, Steiner RD. Risedronate in children with osteogenesis imperfecta: a randomised, double-blind, placebo-controlled trial. Lancet. 2013 Oct 26;382(9902):1424-32
14: Iglesias E, Jou C, Bou R, Antón J. [Importance of muscle biopsy in the
diagnosis of juvenile dermatomyositis]. An Pediatr (Barc). 2014 Feb;80(2):e25-6.
15: Sarrión P, Sangorrin A, Urreizti R, Delgado A, Artuch R, Martorell L,
Armstrong J, Anton J, Torner F, Vilaseca MA, Nevado J, Lapunzina P, Asteggiano CG, Balcells S, Grinberg D. Mutations in the EXT1 and EXT2 genes in Spanish patients with multiple osteochondromas. Sci Rep. 2013;3:1346.
16: Kimura Y, Weiss JE, Haroldson KL, Lee T, Punaro M, Oliveira S, Rabinovich E, Riebschleger M, Antón J, Blier PR, Gerloni V, Hazen MM, Kessler E, Onel K, Passo MH, Rennebohm RM, Wallace CA, Woo P, Wulffraat N; Childhood Arthritis Rheumatology Research Alliance Carra Net Investigators. Pulmonary hypertension and other potentially fatal pulmonary complications in systemic juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2013 May;65(5):745-52.
17: Dolezalova P, Price-Kuehne FE, Özen S, Benseler SM, Cabral DA, Anton J, Brunner J, Cimaz R, O’Neil KM, Wallace CA, Wilkinson N, Eleftheriou D, Demirkaya E, Böhm M, Krol P, Luqmani RA, Brogan PA. Disease activity assessment in childhood vasculitis: development and preliminary validation of the Paediatric Vasculitis Activity Score (PVAS). Ann Rheum Dis. 2013 Oct;72(10):1628-33.
18: Ter Haar N, Lachmann H, Özen S, Woo P, Uziel Y, Modesto C, Koné-Paut I, Cantarini L, Insalaco A, Neven B, Hofer M, Rigante D, Al-Mayouf S, Touitou I, Gallizzi R, Papadopoulou-Alataki E, Martino S, Kuemmerle-Deschner J, Obici L, Iagaru N, Simon A, Nielsen S, Martini A, Ruperto N, Gattorno M, Frenkel J; Paediatric Rheumatology International Trials Organisation (PRINTO) and the Eurofever/Eurotraps Projects. Treatment of autoinflammatory diseases: results from the Eurofever Registry and a literature review. Ann Rheum Dis. 2013 May;72(5):678-85.
19: Gerss J, Roth J, Holzinger D, Ruperto N, Wittkowski H, Frosch M, Wulffraat N, Wedderburn L, Stanevicha V, Mihaylova D, Harjacek M, Len C, Toppino C, Masi M, Minden K, Saurenmann T, Uziel Y, Vesely R, Apaz MT, Kuester RM, Elorduy MJ, Burgos-Vargas R, Ioseliani M, Magni-Manzoni S, Unsal E, Anton J, Balogh Z, Hagelberg S, Mazur-Zielinska H, Tauber T, Martini A, Foell D; Paediatric Rheumatology International Trials Organization (PRINTO). Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study. Ann Rheum Dis. 2012 Dec; 71(12): 1991-7..
20: Heiligenhaus A, Foeldvari I, Edelsten C, Smith JR, Saurenmann RK, Bodaghi B, de Boer J, Graham E, Anton J, Kotaniemi K, Mackensen F, Minden K, Nielsen S, Rabinovich EC, Ramanan AV, Strand V; Multinational Interdisciplinary Working Group for Uveitis in Childhood. Proposed outcome measures for prospective clinical trials in juvenile idiopathic arthritis-associated uveitis: a consensus effort from the multinational interdisciplinary working group for uveitis in childhood. Arthritis Care Res (Hoboken). 2012 Sep;64(9):1365-72.
21: Márquez Balbás G, González-Enseñat MA, Vicente A, Creus-Vila L, Antón J, Umbert-Millet P. Incontinentia pigmenti and bipolar aphthosis: an unusual
combination. ISRN Dermatol. 2011;2011:814186.
22: Antón J. [Autoinflammatory syndromes]. Med Clin (Barc). 2011 Jan;136 Suppl 1:3-9.
23: Koné-Paut I, Darce-Bello M, Shahram F, Gattorno M, Cimaz R, Ozen S, Cantarini L, Tugal-Tutktun I, Assaad-Khalil S, Hofer M, Kuemmerle-Deschner J, Benamour S, Al Mayouf S, Pajot C, Anton J, Faye A, Bono W, Nielsen S, Letierce A, Tran TA; PED-BD International Expert Committee. Registries in rheumatological and musculoskeletal conditions. Paediatric Behçet’s disease: an international cohort study of 110 patients. One-year follow-up data. Rheumatology (Oxford). 2011 Jan;50(1):184-8.
24: Modesto C, Antón J, Rodriguez B, Bou R, Arnal C, Ros J, Tena X, Rodrigo C, Rotés I, Hermosilla E, Barceló P. Incidence and prevalence of juvenile idiopathic arthritis in Catalonia (Spain). Scand J Rheumatol. 2010 Nov;39(6):472-9.
25: Ruperto N, Ozen S, Pistorio A, Dolezalova P, Brogan P, Cabral DA, Cuttica R, Khubchandani R, Lovell DJ, O’Neil KM, Quartier P, Ravelli A, Iusan SM, Filocamo G, Magalhães CS, Unsal E, Oliveira S, Bracaglia C, Bagga A, Stanevicha V, Manzoni SM, Pratsidou P, Lepore L, Espada G, Kone-Paut I, Zulian F, Barone P, Bircan Z, Maldonado Mdel R, Russo R, Vilca I, Tullus K, Cimaz R, Horneff G, Anton J, Garay S, Nielsen S, Barbano G, Martini A; Paediatric Rheumatology International Trials Organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura,
childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part I: Overall methodology and clinical characterisation. Ann Rheum Dis. 2010 May;69(5):790-7.
26: Moorthy LN, Peterson MG, Baratelli M, Hassett AL, Lehman TJ; International SMILEY Collaborative Group. Preliminary cross-cultural adaptation of a new pediatric health-related quality of life scale in children with systemic lupus erythematosus: an international effort. Lupus. 2010 Jan;19(1):83-8.
27: Serrano M, Ormazábal A, Antón J, Aróstegui JI, García-Cazorla A.
Cerebrospinal fluid neopterin and cryopyrin-associated periodic syndrome. Pediatr Neurol. 2009 Dec;41(6):448-50.
28: Marín-Valencia I, Antón J, Ros J, Cols M. Severe generalized oedema with
haemodynamic instability in a previously healthy patient (Case Presentation).
Acta Paediatr. 2009 Mar;98(3):420, 600-1.
29: von Bernuth H, Picard C, Jin Z, Pankla R, Xiao H, Ku CL, Chrabieh M, Mustapha IB, Ghandil P, Camcioglu Y, Vasconcelos J, Sirvent N, Guedes M, Vitor AB, Herrero-Mata MJ, Aróstegui JI, Rodrigo C, Alsina L, Ruiz-Ortiz E, Juan M, Fortuny C, Yagüe J, Antón J, Pascal M, Chang HH, Janniere L, Rose Y, Garty BZ, Chapel H, Issekutz A, Maródi L, Rodriguez-Gallego C, Banchereau J, Abel L, Li X, Chaussabel D, Puel A, Casanova JL. Pyogenic bacterial infections in humans with MyD88 deficiency. Science. 2008 Aug 1;321(5889):691-6.
30: de Carpi JM, Castejón E, Masiques L, Vilar P, Antón J, Varea V.
Gastrointestinal involvement in pediatric polyarteritis nodosa. J Pediatr
Gastroenterol Nutr. 2007 Feb;44(2):274-8.
31: Mou SS, Punaro L, Antón J, Luckett PM. Severe systemic hypersensitivity
reaction to ibuprofen: a presentation of systemic lupus erythematosus. J
Rheumatol. 2006 Jan;33(1):171-2.
32: Ozen S, Anton J, Arisoy N, Bakkaloglu A, Besbas N, Brogan P, García-Consuegra J, Dolezalova P, Dressler F, Duzova A, Ferriani VP, Hilário MO, Ibáñez-Rubio M, Kasapcopur O, Kuis W, Lehman TJ, Nemcova D, Nielsen S, Oliveira SK, Schikler K, Sztajnbok F, Terreri MT, Zulian F, Woo P. Juvenile polyarteritis: results of a multicenter survey of 110 children. J Pediatr. 2004 Oct;145(4):517-22.
Estudio multicéntrico, aleatorizado, de grupos paralelos, controlado con placebo, doble ciego para evaluar la seguridad, eficacia y farmacocinética de belimumab, un anticuerpo monoclonal humano anti-BLyS, más terapia estándar en pacientes pediátricos con lupus eritematoso sistémico (LES)
Promotor: GlaxoSmithKline S.A.
Código del protocolo: BEL114055
Función: Investigador Principal
“Estudio fase III, multicéntrico, abierto, para evaluar la farmacocinética, eficacia y seguridad de abatacept administrado por vía subcutánea (s.c.) en niños y adolescentes con artritis idiopática juvenil poliarticular (AIJp) activa y respuesta inadecuada (RI) a fármacos antirreumáticos modificadores de enfermedad (FAME) biológicos o no biológicos”
Promotor: Bristol- Myers-Squibb
Códigodel protocolo: IM101-301
Función: Investigador Principal
“Estudio de fase Ib, multicéntrico, abierto, para investigar la farmacocinética, farmacodinamia y seguridad de tocilizumab tras administración subcutánea a pacientes con artritis idiopática juvenil poliarticular”
Promotor: Roche
Código del protocolo: WA28117
Función: Investigador Principal
SHARE: Single Hub and access point for Paediatric Rheumatology in Europe
Entidad financiadora: SANCO 2011, section 3.2.3.3, FP7 call 2011 Second Programme of Community action in the field of Health (2008-2013). Executive Agency for Health and Consumers, EAHC (European Union)
Duración: 2012-2015
Financiación (en miles de euros): 860.244 euros
Investigador: colaborador
Incidencia de mutaciones somáticas del gen NLRP3 en pacientes con diagnóstico clínico compatible con síndromes periódicos asociados a la criopirina
Función: Investigador Principal
Agencia financiadora: Beca Sociedad Catalana de Reumatología
Financiación: 6000 euros
Duración: Junio 2012-Junio 2014
EPOCA (EPidemiology, treatment and Outcome of Childhood Arthritis)
Función: Investigador Principal Hospital Sant Joan de Déu
Agencia financiadora: PRINTO (Pediatric Rheumatology Trials Organization)
Duración: 2011-2014
Evaluation of Early Treatment in Children With Juvenile Idiopathic Arthritis: A Retrospective Analysis
Función: Investigador Principal
Agencia Financiadora: Pfizer
Financiación: 55.413 €
Duración: 2011-2013
PHARMACHILD – Long-term PHARMacovigilance for Adverse effects in Childhood arthritis focussing on Immune modulatory drugs a Pediatric Rheumatology Trials Organization (PRINTO) / Pediatric Rheumatology European Society (PRES) registry
Función: Investigador Principal Hospital Sant Joan de Déu
Agencia Financiadora: FP7- HEALTH-2010-single-stage. EU grant (2011-2014): (project number 260353)
Financiación: 3.920.000 € (2.970.000€ funded by FP7)
Duración: 2011-2014 (36 months)
Study CACZ885G2305. A randomized , double blind, placebo controlled, single-dose study to assess the initial efficacy of canakinumab (ACZ885) with respect to the adapted ACR pediatric 30 criteria in patients with Systemic Juvenil Idiopathic Arthritis(SJIA) and active systemic manifestations.
Financiación: Novartis.
Investigador: Principal
Duración: 2009-2010
Study CACZ885G2301. A randomized, double-blind, placebo controlled, withdrawal study of flare prevention of canakinumab (ACZ885) in patients with Systemic Juvenile Idiopathic Arthritis (SJIA) and active systemic manifestations.
Financiación: Novartis.
Investigador: Principal
Duración: 2009-2010
Study CACZ885G2301E1. An open label study of canakinumab (ACZ885) in patients with Systemic Juvenile idiopathic arthritis (SJIA) and active systemic manifestations.
Financiación: Novartis.
Investigador: Principal
Duración: 2009-2012
CLIPPER. A 2-Part Open-Label Study to Assess the Clinical Benefit and Long-term Safety of Etanercept in Children and Adolescents with Extended Oligoarticular Juvenile Idiopathic Arthritis, Enthesitis-Related Arthritis, or Psoriatic Arthritis.
Financiación: Wyeth- Pfizer.
Investigador: Principal
Duración: 2010-2012
STRIVE. Long-term, Multi-center, Longitudinal Post-marketing, Observational Registry to Assess Long Term Safety and Effectiveness of HUMIRA® (Adalimumab) in Children with Moderate to Severe Active Polyarticular or Polyarticular Course Juvenile Idiopathic Arthritis (JIA)
Financiación: Abbott.
Investigador: Principal
Duración: 2010-2020
Estudio piloto, abierto, multicéntrico, de eficacia y seguridad del tratamiento con canakinumab duranet 6 meses y seguimiento de hasta 6 meses, en pacientes con síndrome Hiper-IgD activo.
Financiación: Novartis.
Investigador: Principal
Duración: 2011-2012.
INternational CHildhood ARthritis GEntics (INCHARGE) Consortium: A Genome Wide Association Study of Childhood Arthritis.
Función: Investigador Principal Hospital Sant Joan de Déu
Agencia financiadora: Arthritis Research campaign: ARC grant reference 17552.
Duración: 2008-(sin limite en la actualidad)
Número de Proyecto: PI06/0241
The PRES European Network of Registries for Autoinflammatory Diseases in childhood: EuroFever Project
Función: Investigador principal Hospital Sant Joan de Déu
Agencia Financiadora: Agency for Health and Cosnumers EAHC, Project Nº 2007332)
Financiación: 341.733,46 €
Duración: 2008-2011(36 meses)
Estudio de correlación entre los factores clínicos y polimorfismos genéticos para el desarrollo y severidad de la uveítis asociada a la artritis idiopática juvenil (AIJ).
Función: Investigador Principal Hospital Sant Joan de Déu
Agencia financiadora: Hospital Clinic – Hospital Sant Joan de Déu
Duración: 2008-2011
Phase III. A Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel Group Study of One year Duration Followed by 2 Years of Open-label Treatment to Determine the Safety and Efficacy of Orally Administered 2.5 mg or 5.0 mg Daily Risedronate (risedronate sodium), in Children > 4 to < 16 Years Old with Osteogenesis Imperfecta. 2006
Función: Investigador Principal Hospital Sant Joan de Déu
Agencia Financiadora: Warner Chilcott – Procter and Gamble – Sanofi-Aventis
Duración: 3 años (2006-2010)
Cross cultural validation of a novel quality of life scale for pediatric lupus – proposal and update
Función: Investigador Principal Hospital Sant Joan de Déu
Agencia Financiadora: UMDNJ Foundation Grant 2004-2005; Pfizer Clinical Scholar Research Award 2005-2007; Arthritis Foundation Investigator Award 2007-2009; CARRA
Duración: 4 años (2006-2009)
Número de Proyecto: PS09/01182
Título: Análisis de las vías de señalización Toll/IL-1 receptor (TIR), Nod-like receptor (NLR) y NF-κB en las formas hereditarias y no hereditarias de las enfermedades autoinflamatorias. Valoración de su utilidad clínica como pruebas predictivas de respuesta a terapias biológicas.
Entidad financiadora: Fondo de Investigaciones Sanitarias
Duración: 2010-2012
Centro: Hospital Clínic de Barcelona – Hospital Sant Joan de Déu
Investigador principal: Jordi Yagüe Ribes
Investigador: Colaborador
Phase III. A Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel Group Study of One year Duration Followed by 2 Years of Open-label Treatment to Determine the Safety and Efficacy of Orally Administered 2.5 mg or 5.0 mg Daily Risedronate (risedronate sodium), in Children > 4 to < 16 Years Old with Osteogenesis Imperfecta. 2006
Obejtivos: Valoración de la seguridad y eficacia del tratamiento con risedronatoen pacientes con Osteiogénesis Imperfecta
Finaciación: Industria farmaceutica
Centro: Multicéntrico Internacional
Investigador: colaborador
Duración: 3 años (2006-2010)
Número de Proyecto: PI06/0241
Título: Análisis de las bases moleculares responsables de las enfermedades autoinflamatorias sistémicas no filiadas: desarrollo y validación de pruebas diagnósticas e identificación de potenciales dianas para terapias biológicas inmunomoduladoras.
Entidad financiadora: Fondo de Investigaciones Sanitarias
Duración: 2007-2009
Centro: Hospital Clínic de Barcelona – Hospital Sant Joan de Déu
Investigador principal: Jordi Yagüe Ribes
Investigador: Colaborador
Cross cultural validation of a novel quality of life scale for pediatric lupus – proposal and update
Objetivos: validación de una escala clínica para la valoración de la calidad de vida en pacientes con Lupus
Financiación: No
Centro: Multicéntrico Internacional
Investigador: colaborador
Duración: 4 años (2006-2009)
A randomised trial of 6 months versus 12 months withdrawal of methotrexate (MTX) in patients with juvenile idiopathic arthritis (JIA) in clinical remission
Objetivos: Valorar la duración de la remisión clínica tras la retirada del metotrexate a los 6 meses o a los 12 meses en pacientes con Artritis Idiopática Juvenil
Financiación: PRINTO (Pediatric Rheumatology Trials Organization)
Centro: Multicéntrico Internacional
Investigador: Colaborador
Duración: 3 años (2006-2008)
Artritis inflamatòries de la infància: estudi prospectiu de la seva incidència i prevalença a Catalunya
Objetivo principal: Conocer la incidencia y prevalencia de las artritis inflamatorias en la infancia en Catalunya
Finaciación: Beca Marató de TV3
Centro: Hospital Vall d’Hebron – Hospital Sant Joan de Déu
Investigador: Colaborador
Duración: 3 años (2004-2007)
Inception cohort for early juvenile systemic sclerosis
Objetivos: Creation of a minimal gold standard for avalauation of patients with juvenile systemic sclerosis
Financiación. No
Centro: Multicéntrico internacional
Investigador: Colaborador
Date full C.V. last updated: August 29th 2014
This abridged C.V. represents an accurate summary of my current C.V.
Signature of Investigator Date: August 29th 2014
Shai Ashkenazi
Tel Aviv University
Israel
Shai Ashkenazi completed his medical education and residency in pediatrics in Israel and a fellowship in pediatric infectious diseases in Houston, Texas, USA (1987-90). He is currently Professor of Pediatrics and Incumbent of the Lea and Arieh Pickel Chair for Pediatric Research at the Sackler Faculty of Medicine, Tel Aviv University; Chairman of the Department of Pediatrics A at Schneider Children’s Medical Center; Head of the Research Laboratory for Pediatric Infectious Disease at the Felsenstein Medical Research Center, Chairman of the Israeli Scientific Council, Chair of the Education Committee of the European Society for Paediatric Infectious Diseases, member of the Scientific Committee of the World Society for Pediatric Infectious Diseases, and member of the National Council for Child Health.
Dr Ashkenazi is a member of the Editorial Boards of several national and international medical journals, a co-author of over 200 medical publications and over 30 chapters in books and the Editor of the Hebrew Textbook of Pediatrics (8 editions). He has received dozens of research grants, including from the NIH (USA), European Union, Chief Scientist and the BSF.
Sami Bahna
LSU Health Sciences Center
USA
Prof. Sami L. Bahna is professor of pediatrics and medicine and chief of the Allergy/Immunology Section at Louisiana State University School of Medicine in Shreveport, Louisiana. He graduated and completed his PhD in Egypt. He serves on numerous international committees and has received multiple distinguished awards. He has been an invited speaker to many international scientific meetings. Dr. Bahna served on several NIH committees and three terms on the Executive Committee of the AAP-Section on Allergy & Immunology. He is author or co-author of more than 270 publications and he is frequently invited as visiting professor at major institutions and speaker at major national and international meetings.
Ami Ballin
Tel Aviv University
Israel
Dr. Ami Ballin
Graduated from the Sackler School of Medicine, Tel-Aviv University (1976) and is board certified in Pediatrics, Hematology and Pediatric Hemato-oncology. He did a fellowship at the Hospital for Sick Children (1985-1987) and currently is the head of the Pediatrics department at the E. Wolfson Medical Center, Israel.Dr. Ballin is Professor in Pediatrics and vice-Dean of the Sackler School of Medicine. He is the chairman of the Committee of Professionalism at the Sackler School of Medicine. Dr. Ballin was the medical director of the Israeli National Umbilical Cord Blood Bank and formerly the chairman of the Israeli Clinical Pediatric Society.
Mark Beattie
University Hospital Southampton
UK
Prof. Mark Beattie is a Consultant Paediatric Gastroenterologist in Southampton and the lead for the regional service. His main clinical and research interests include the Nutritional Management of Chronic Disease, particularly Inflammatory Bowel Disease. He is the clinical lead in the Southampton Genetics Paediatric IBD Research team. He has published widely in the area of Paediatric Gastroenterology and he is the author of multiple revision texts, and the Oxford Handbook of Paediatric gastroenterology, Hepatology and Nutrition. He was President of the British Society of Paediatric Gastroenterology, Hepatology and Nutrition from 2010-3 and Editor in Chief of Archives of Disease in Childhood 2012-7.
Marc A. Benninga
University of Amsterdam
The Netherlands
Prof. Marc Benninga studied medicine at the University of Amsterdam, the Netherlands. After receiving his Medical degree he worked as a research fellow at the department of paediatric gastroenterology and nutrition at the Academic Medical Centre in Amsterdam. He performed extensive research on constipation and faecal incontinence in childhood. After his paediatric training in the Wilhelmina Children’s Hospital in Utrecht, he performed research at The Women’s and Children’s Hospital, Adelaide, Australia. During his stay in Adelaide his research focussed on maturation of upper gastrointestinal motility in very young infants. In 1999 he became a staff member in the Academic Medical Centre in Amsterdam and currently he is the head of the department paediatric gastroenterology & nutrition. The focus of his current clinical and research work is gastro-oesophageal reflux disease, recurrent abdominal pain, functional defecation disorders and inflammatory bowel disease in childhood.
Itai Berger
Hadassah Medical Center
Israel
Dr. Itai Berger
Specialist in Pediatric Neurology and Child Development. Serves as the Director of the Neuro-Cognitive Center, and the Pediatric Neurology Unit at Hadassah-Hebrew University Medical Center. Senior Lecturer at the Hebrew University School of Medicine. Primary clinical and research interests involve early brain development, the factors affecting it (both genetic and environmental) and the impact on long-term neuro-developmental outcome with special focus on cognitive (higher) functions and on fetal and neonatal neurology.
Patrick Bontems
Queen Fabiola Children’s University Hospital
Belgium
Patrick BONTEMS, MD, PhD, born in 1965, is Professor and Head of the Department of Paediatric Gastroenterology at the Université Libre de Bruxelles. He works at the Hôpital Universitaire des Enfants Reine Fabiola, at the Academic Hospital Erasme and at the Universitiy Hospital Tivoli. He has published many original studies on gastro-duodenal mucosal diseases and immunological responses, on inflammatory bowel diseases and on nutritional screening. He is member of different scientific societies: European Society of Paediatric Gastroenterology, Hepatology and Nutrition – European Crohn and Colitis Organisation – Vice-President of the Belgian Society of Paediatric Gastroenterology, Hepatology and Nutrition – President of the Belgian Helicobacter and microbiota Study Group.
Xavier Bosch
Health University Barcelona Camus
Spain
Dr. F. Xavier Bosch conducts epidemiological research on cancers linked to infectious agents notably on cancer of the liver, of the cervix, of the skin, of the vagina, of the anus, of the penis and of the oral cavity. He has also carried on research studies on diet and colorectal cancer and led a program of implementation and methodological research in cancer registration.
These various research projects have been instrumental in demonstrating the causal role of Human Papilloma Virus (HPV) in cervical cancer and on the opportunities for liver cancer prevention using Hepatitis B Virus (HBV) vaccines in rural Africa. Some of these studies have played a catalytic role for the initiation of the first vaccine trials for HBV and HPV and for the evaluation of HPV tests as screening tools. Dr. F. Xavier Bosch has worked in what is now called molecular epidemiology. His research work has been characterized by the integration of the latest biological assays to determine exposure to carcinogens with epidemiological field studies carried out in about 35 countries around the world, particularly in Spain, Latin America, Africa and Asia. The final goal of his research has been the application of the aetiological knowledge derived from it, to the primary prevention of cancer.
Per Brandstrom
Queen Silvia Childrens’ Hospital
Sweden
Per Brandström MD, PhD
From 1993 he worked as a pediatrician at Jönköping county hospital. Since 2013 he has been working with pediatric nephrology in Gothenburg, one of four tertiary pediatric nephrology centers in Sweden. Doctoral thesis on the Swedish Reflux Trial in 2010 and in his scientific work he has continued to focus on urinary tract infection and vesicoureteral reflux, together with his collaborates at the Pediatric Uro-Nephrologic Center in Gothenburg.
Chairman of the Swedish Society of Pediatric Nephrology since 2013.
Jan Buitelaar
University Nijmegen Medical Centre
The Netherlands
Jan Buitelaar is a professor of psychiatry and child and adolescent psychiatry at the Radboud University Nijmegen Medical Centre, and at the Donders Institute for Brain, Cognition and Behaviour in Nijmegen, The Netherlands. He is also head of Karakter Child and Adolescent Psychiatry University Centre in Nijmegen. He has a strong clinical and research interest in neuropsychiatric disorders as ADHD, autism and impulsivity and aggression related disorders, and has been involved in pharmacological, cognitive, clinical, genetic, and neuroimaging studies in these disorders. His current active research is focused on translational studies aiming to identify new molecular targets for ADHD and autism through matching preclinical models to human imaging genetics studies. His research is supported by grants from the European Union (programmes TACTICS, Aggressotype, MATRICS, EU-AIMS, MiND, BRAINVIEW, IMAGEMEND, CoCA), NIH, and from the Dutch Medical Research Council. He has been editor in chief of European Child and Adolescent Psychiatry for the last 10 years. He has published around 700 peer-reviewed scientific papers.
Georges Casimir
Queen Fabiola Children’s University Hospital
Belgium
Georges CASIMIR
Member of the Royal Academy of Medicine of Belgium
Professor of Pediatrics, Université libre de Bruxelles (ULB)
Chief Medical Officer University Children Hospital Queen Fabiola
Vice Dean for Education and International Relations, Faculty of Medicine, Université libre de Bruxelles
Advisor for hospital policy of the Chairman of the Board of Officers and the Rector, Université libre de Bruxelles
Head of Pulmonology and Cystic Fibrosis department, Queen Fabiola Children’s University Hospital
Secretary of the Belgian Kids Foundation for Pediatric Research
Past President of the Belgium Academy of Pediatrics
Author of more than 100 scientific (topics : allergy, cystic fibrosis, inflammation)
Member of the Editorial Board of many medical Journal
Quinquennial Prize 2006-2011 of Medical sciences from the Belgium Government
Invited Professor of the Tokyo Women University
Gold Medal of the State University of Armenia 2013
Rolando Cimaz
University of Florence
Italy
Cimaz Rolando Born in Milan, Italy, November 21st 1961Graduated in Medicine and Surgery Magna Cum Laude from Università degli Studi di Milano on July 20th, 1987Specialized in Pediatrics from the University of Milano in July 1991Specialized in Rheumatology from the University of Milano in November 2003Medical intern from 1984 at the First Pediatric Dpt of University of MilanoQualified to practice Medicine in USA (Foreign Medical Graduates Examination in the Medical Sciences);
Clinical Fellow (September 93 to September ‘94) in Pediatric Rheumatology at The University of Texas Southwestern Medical School, Dallas, Tx, USA (Prof CW Fink)
Worked at the Clinica Pediatrica G e D De Marchi of Milano University, 1995-2005
Visitor, Prof BM Ansell, UK, June 1998
Visiting Professor, University of Lubiana, 1999
Visiting Professor, University of British Columbia (prof R Petty, July, August 2000)
Executive committee member and cofounder, Pediatric Rheumatology European Society
Maitre des Conferences- Praticien Hospitalier. Universitè Lyon 1- Hospices Civiles de Lyon, Lyon, France, 2005-2006
Dirigente Medico (dal 1 Marzo 2007) and Professore Associato Università di Firenze (dal 1-12-2007), Osp. Meyer Firenze
Tamás Constantin
Semmelweis University
Hungary
Dr. Tamás Constantin graduated from the University of Debrecen and is board certified in Paediatrics, Rheumatology. He did a fellowship at the Semmelweis University and currently is the head of the Unit of Paediatric Rheumatology at the 2nd Department of Paediatrics, Semmelweis University. Dr. Constantin is the chairman of the Hungarian Paediatric Rheumatology Association. His current active research is focused on possible neuro-psychiatric side effects of biologicals.
Justin De Jong
Pediatric Surgical Center Amsterdam
The Netherlands
Justin R. de Jong, MD PhD, pediatric surgeon; staff member of the Pediatric Surgical Center of Amsterdam (Academic Medical Center /VU Medical Center), the Netherlands.
He was one of the pediatric surgeons who developed the laparoscopic and thoracoscopic surgical program for neonates and children in Amsterdam.
His special interests are the surgical treatment of inflammatory bowel disease, anorectal malformations, Hirschsprungs disease, pseudoobstruction, motility disorders; thoracic wall deformities and pediatric traumatology
Tom P.V.M. de Jong
University Children’s Hospitals UMC & AMC
The Netherlands
Anthony E.J. Dubois
University Medical Center Groningen
The Netherlands
Professor Dubois obtained his medical degree from the Free University Amsterdam in 1978. From 1979 to 1984 he completed his PhD at McGill University, Montreal in tumor immunology and was awarded the degree in 1987. He went on to train in Internal Medicine at McGill University in Montreal in 1984 and completing the training in 1988 at McMaster University in Hamilton, Canada. He then completed the training in Allergy and Clinical Immunology at the University of Western Ontario, London, Canada in 1991 and relocated to the Netherlands where he obtained a full time academic position in the Department of Allergy at University Medical Center, Groningen. He was appointed full professor of Pediatric Allergy in 2005. His main area of research has been food allergy, having established the first Food Challenge Unit for routine care in his country in 2001
Christian Gluud
Copenhagen University Hospital
Denmark
Christian Gluud is Danish. He became M.D. in 1976 and Dr. Med. Sci. in 1988. He has been in charge of a large number of randomised clinical trials and systematic reviews, including meta-analysis and Trial Sequential Analysis. He is specialist in internal medicine, gastroenterology, and hepatology. Since 1995 he is Head of the Copenhagen Trial Unit, Centre for Clinical Intervention Research, Rigshospitalet, Copenhagen University Hospital. He is Co-ordinating Editor of The Cochrane Hepato-Biliary Group. He has produced more than 550 publications.
Rafael Gorodischer
Ben-Gurion University
Israel
Rafael Gorodischer
MD University of Chile Medical School, 1964
Present academic position: Professor of Pediatrics (Emeritus), Ben Gurion University of the Negev, Beer- Sheba, Israel
Pediatric Residency: Department of Pediatrics, Children’s Hospital of Buffalo, Buffalo, New York, USA, 1965-1967
Further specialty training: Research/ Postdoctoral fellow in Metabolic Diseases and Developmental Pharmacology, Department of Pediatrics, State University of New York at Buffalo School of Medicine, Buffalo, New York, USA, 1967- 1969
Certifications:
Diplomate American Academy of Pediatrics, 1970
Specialist in Clinical Pharmacology, Israel, 1998
Israel Clinical Pediatric Society, The Pediatrician of the Year Award, 2007
The Best Reviewer for the journal “Pharmacoepidemiology and Drug Safety”, 2011
Positions held:
Director Department of Pediatrics, Negev Central Hospital/ Soroka University Hospital, Beer- Sheba, Israel, 1971- 2004
President, European Society for Developmental, Perinatal and Pediatric Pharmacology, 1998- 2001
Professional Sabbatical Leaves:
Visiting Scientist, Food and Drug Administration, Metabolism Branch, Washington, D.C., USA, 1985- 1986
Visiting Professor, Medical School, University of Toronto and Division of Clinical Pharmacology, The Hospital for Sick Children, Toronto, Canada, 1992-1993
Visiting Professor, Departments of Pharmacology and of Pediatrics, Medical School, University of Chile, Santiago, Chile, 2005
Present position: Patient Safety and Risk Management Unit, Soroka University Medical Center, Beer-Sheba, Israel
Jaap Groothoff
The Netherlands
Ulrich Heininger
University of Basel
Switzerland
Ulrich Heininger has been in charge of the Division of Paediatric Infectious Diseases and Vaccinology at the University Children’s Hospital in Basel, Switzerland, since 1998.
He is a professor of paediatrics at the University of Basel and his research is focused on vaccine-preventable diseases, vaccines, and vaccine safety. He is one of the founding members of „The Brighton Collaboration“, an international collaboration of volunteers aiming at standardization of adverse events following immunization. Currently, Ulrich Heininger serves a member of the Global Advisory Committee on Vaccine Safety (GACVS) of the World Health Organization.
He is one of 8 scientists and founding member running the INFOVAC service, a Swiss nationwide information network for vaccine related questions raised by physicians in private practice.
Ulrich Heininger has been appointed to the National Immunization Recommendation Boards of Germany in 2001 and of Switzerland in 2004, respectively, and has been a member of these committees ever since; further, he has been board member (treasurer) of ESPID from 1999 to 2005 and was president of ESPID from 2009 to 2012.
He serves on the editorial board of several journals, including Pediatric Infectious Disease Journal (Chief Associate Editor) and Archives of Disease in Childhood, and has published more than 250 scientific publications in the field of paediatric infectious diseases and vaccines. Ulrich Heininger is editor and co-editor of several standard textbooks in the field of vaccinology and paediatric infectious diseases and has written numerous chapters in national and international paediatric textbooks.
J.Hans Hoekstra
Hieronymus Bosch Hospital
The Netherlands
J.Hans Hoekstra is a pediatric gastroenterologist from the Hieronymus Bosch Teaching Hospital in ’s-Hertogenbosch, The Netherlands. After a pediatric training in Groningen he had his pediatric gastroenterology fellowship in Montreal (Hopital Ste. Justine)
His research concerned chronic diarrhea and acute gastroenteritis. He is an active member of the ESPGHAN (European Society for Pediatric Gastroenterology, Hepatology, and Nutrition) and was chairman of the working group on acute gastroenteritis. In this respect he was one of the members of the group that published the first ESPGHAN/ESPID Evidence-Based Guidelines on the management of acute gastroenteritis in children. Currently he is co-chair of the pediatric working group for recommendations for the use of probiotics in the Asian-Pacific region.
Jessie Hulst
Erasmus MC
The Netherlands
Dr. Jessie Hulst is a staff member at the Department of Pediatric Gastroenterology, Hepatology & Nutrition of Erasmus Medical Centre, Sophia Children’s Hospital, Rotterdam, the Netherlands since 2011. She received her medical education at Erasmus University of Rotterdam. She completed a residency in pediatrics and a fellowship in pediatric Gastroenterology, Hepatology and Nutrition at Erasmus Medical Centre, Sophia Children’s Hospital, Rotterdam. She completed her PhD-thesis on nutritional assessment in critically ill infants and children in 2004. Her current research focuses on malnutrition, screening for malnutrition, and nutrition, nutritional status and body composition in relation to disease in various patient groups (e.g. intensive care, intestinal failure, cystic fibrosis).
Dr Hulst is a member of the Committee on Nutrition of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the chair of its working group on Clinical malnutrition. She is also the chair of the paediatric section of the National Steering group Malnutrition, and the chair of Nutritional Committee of Sophia Children’s Hospital. Furthermore, she is a member of the scientific committee of the European Society of Cystic Fibrosis (ECFS) and a member of the National Platform healthy nutrition for children aged 0-4 years and the Nutritional Committee of the Dutch Paediatric Association.
Hans-Iko Huppertz
Klinikum Bremen-Mitte
Germany
Dr. med. Hans-Iko Huppertz
graduated from Würzburg medical school in 1979
received the degree “Dr. med” by work on the polypeptide composition of mumps
virus in 1979 (mentor: Volker ter Meulen)
resident in surgery and obstetrics 1979-1981
work in a rural hospital in Rwanda, Central Africa 1982-1984 resident in
pediatrics at Würzburg university hospital 1984-1988
state certified pediatrician in 1988
work at the University of British Columbia in Vancouver, Canada in medical
microbiology and pediatric rheumatology with a grant from the German Research
Association 1988-1990
staff pediatrician and consultant of pediatrics at Würzburg university hospital 1990- 1999, since 1996 vice chairman
lecturer in pediatrics with a thesis on the possible infectious etiology of chronic arthritis in children in 1992
head of a research laboratory and organizer of several multicenter-studies in pediatric rheumatology and infectious diseases
head of pediatrics at the Klinikum Bremen-Mitte (Prof.-Hess-Kinderklinik) since 1999 affiliation with the University of Göttingen, Germany
state certified in pediatric infectious diseases and in pediatric rheumatology president of the 101st annual meeting of the German Society of Pediatrics 2005
president of the North German Society of Pediatrics since 2007. Member of several committees at the German Society/Academy of pediatrics.
associate editor, member of editorial boards and referee for several journals in pediatrics, drugs in children, infectious and rheumatic diseases research interests in pediatric infectious diseases, pediatric rheumatic diseases, pediatric drugs
Koen Joosten
University in Leuven
The Netherlands
Dr Koen F.M. Joosten, M.D., PhD
Koen Joosten is paediatric-intensivist and associated Professor paediatrics at ErasmusMC-Sophia Children’s Hospital, in the Netherlands. Dr K. Joosten studied medicine at the Radboud University in Nijmegen, the Netherlands and became a paediatrician in 1993. In 1995 he did his training as a paediatric-intensivist at ErasmusMCSophia Children’s Hospital and in 1999 received his PhD, which focused on metabolism, endocrinology and nutrition of the critically ill child. He continued research activities in this field and has supervised many PhD projects in nutrition and metabolism including. Part of his research activities are carried out in collaboration with the Catholic University in Leuven, Belgium, the Pediatric Intensive Care, Stollery’s Childrens Hospital, Edmonton, Alberta, Canada and Boston Children’s Hospital. Together with Dr Jessie Hulst, he developed a new simple nutritional (risk) screening tool, named STRONGkids. In 2008, in a nationwide campaign in collaboration with the Dutch government, a performance indicator for screening and treatment of children admitted to the hospital was implemented. Dr Joosten is a member of several nutritional committees; is chairman of the feeding group of the Dutch Paediatric Association, chairman of the Task Force group healthy feeding children 0-4 year, member of the Dutch steering committee on malnutrition, and is treasurer of the Netherlands Society of Parenteral and Enteral Nutrition. He is an ESPEN lecturer of LLL courses. He has published more than 150 peer-reviewed articles and given several lectures primarily on the topic of screening and feeding the ill child in the international arena. He is associate editor of Clinical Nutrition.
Joana Kist-van Holthe
VU University Medical Center
The Netherlands
Joana Kist-van Holthe MD PhD is a pediatrician with a passion for research. After 25 years clinical experience as a pediatric nephrologist and as an allround pediatrician, she decided it was time to change her career and spend more time on research. Her primary interest is Childhood Public Health. In 2010 she started to work at the Amsterdam Public Health research institute, VU University Medical Center in Amsterdam, The Netherlands. Currently she participates in research pertaining to cardiovascular risk in obese children.
Sibylle Koletzko
Ludwig Maximilians University Munich
Germany
Professor Dr. Sibylle Koletzko is the Head of Paediatric Gastroenterology and Hepatology, Dr. v. Haunersches Kinderspital, Ludwig Maximilians University Munich, Germany. Her research involves projects in inflammatory bowel disease, coeliac disease, and food allergy. She is one of the principal investigators of the German Infant Nutrition Intervention (GINI Plus) study and the ProCeDE trial (evaluation of the new guidelines for the diagnosis of coeliac disease), the German investigator for a large intervention trial PrevendCD, and member of the coeliac group for the long-term observational TEDDY study.
Sibylle Koletzko served as secretary of GI-committee from 2005-2012 and council member of European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) (2009-2012), and president of the German Society of Paediatric Gastroenterology and Nutrition (GPGE) (2007-2009). She is the chair of the ESPGHAN Working group for Helicobacter pylori infections, and member of the ESPGHAN Porto group for IBD and the Coeliac working group. She presents ESPGHAN in the Scientific Committee of the United European Gastroenterology (UEG). She is past-president of the German speaking Society of Paediatric Gastroenterology and Nutrition (GPGE). She has contributed to several national and international guidelines, including the topics Crohn’s disease, ulcerative colitis, celiac disease, infectious gastroenteritis in childhood, cow’s milk allergy, food allergy, and Helicobacter pylroi infection. She is a member of the Editorial board of the Journal of Pediatric Gastroenterology and Nutrition and is principal author or co-author of >300 scientific publications, book chapters and reviews.
Gideon Koren
Hospital for Sick Children
Canada
Gideon Koren, MD, FRCPC is the founder and director of the Motherisk Program and professor of Paediatrics, Pharmacology, Pharmacy, and Medical Genetics at the University of Toronto.
Author of 1300 peer review scientific papers and editor of over a dozen medical books, Dr. Koren is one of very few Canadian physician-scientists whose career is dedicated to drug safety, the molecular mechanisms and clinical effects of adverse drug and chemical reactions, with specific focus on pregnancy and children.
Dr. Koren has received numerous national and international awards for his work on drug safety. He served as the Chair of the NIH review panel for Obstetric Pharmacology Research Units, and The Hospital for Sick Children’s Foundation Scientific panel on paediatric Complementary and Alternative Medicine. In 2000 Dr. Koren established the Canadian Research Network for Fetal Alcohol Syndrome (“FACE”–Fetal Alcohol Canadian Expertise). In 2002 he created the peer review medical journal Fetal Alcohol Research. Dr. Koren also serves as a paid consultant to Duchesnay.
Meng-Chuan Lai
The Hospital for Sick Children
Canada
Meng-Chuan Lai, MD, PhD is Clinician Scientist and O’Brien Scholar within the Child and Youth Mental Health Collaborative at the Centre for Addiction and Mental Health and The Hospital for Sick Children. He is Assistant Professor in the Department of Psychiatry, University of Toronto. He is also Honorary Director of Gender Research in Autism at the Autism Research Centre of the University of Cambridge, and Adjunct Attending Psychiatrist and Assistant Professor of Psychiatry and Psychology at the National Taiwan University.
Dr. Lai investigates the cognitive and neuro/biological bases of autism and associated neurodevelopmental conditions, and their emerging comorbidities (such as depression, anxiety and medical illness) across the lifespan. A particular focus is on females with autism and the complex relations between autism, sexual differentiation and gender socialization. His research aims to delineate the contributing/moderating roles of sex and gender in the etiology and lifespan development of neurodevelopmental and associated mental health conditions.
Dorit Lev
Wolfson Medical Center
Israel
Dr. Dorit Lev is the Director of the Genetic Institute and the Co-Director of the Metabolic- Neuro-Genetic (Magen) service at the Wolfson Medical Center, Israel. In addition, Dr. Lev is a senior lecturer at the Department of Paediatrics at the Sackler School of Medicine, Tel Aviv University.
Her research focuses mainly on the delineation and identification of genes causing neurogenetic diseases and neuromuscular disorders and other genetic conditions, especially mitochondrial disorders.
Dr Dorit Lev is also a senior lecturer at the Department of Pediatrics at the Sackler School of Medicine, Tel Aviv University.
She has been involved in carrying out clinical and molecular research mainly in the following fields: Delineation of new neurogenetic, neuromuscular syndromes, mitochondrial disorders and neurogenetic fetal abnormalities.
Mike Levin
Imperial College London
UK
Michael Levin is Professor of Paediatrics and International Child Health, at Imperial College London. His research has focused on life threatening infections of childhood. He is the co-ordinator of two European Commission awards – an FP7 award studying the genetic basis of meningococcal and other life threatening bacterial infections of childhood, working with a consortium of colleagues from Europe, African and Singapore (EUCLIDS), and a recently awarded Horizon 2020 award to study Personalised Risk assessment in febrile illness to Optimise Real life Management across the European Union (PERFORM).
Gilat Livni
Schneider Children’s Medical Center
Israel
Gilat Livni completed her residency in Pediatrics and fellowship in Infectious Diseases at Schneider Children’s Medical Center of Israel, and is board-certified. In addition she had training at Evanston Microbiology laboratory in Chicago, USA. Since 2002 Dr. Livni is Deputy Director of Department of Pediatrics and since 2015 head of the section of prevention and treatment of surgical infections, both at Schneider.
Dr. Livni has a keen interest in surgery-related infections. She is vigorously involved in developing and implementing clinical medical education programs designed for medical students and residents alike. Her primary research interests lie in various aspects of pediatric urinary tract infections and immunizations. Dr. Livni has around 50 medical publications and over 500 citations. She is a senior lecturer in Pediatrics at Sackler Faculty of Medicine, Tel Aviv University
Pier Luigi Lopalco
University of Pisa
Italy
Pier Luigi Lopalco, MD, Full Professor of Hygiene and Preventive Medicine at the Pier Luigi Lopalco, MD,ly). He s Full Professor of Hygiene and Preventive Medicine at the University of Pisa (Italy). He started his career in the academic field in Italy, as regional epidemiologist in the Pertussis Project (the largest clinical trial on acellular pertussis vaccines – 1991). Between 2005 and 2015 he joined the ECDC, where has been Head of the Vaccine Preventable Disease Programme. During that period he has contributed to strengthening European collaboration in the field of vaccination programmes and produced several guidance documents to support the decision making process for introduction of new vaccines at national level. Since October 2015 he took back his position in the Italian University, moving to Pisa in April 2016, where he is teaching Epidemiological Methods and Public Health at the School of Medicine. His research activity has been focused on infectious disease epidemiology and prevention, with a special focus on safety and effectiveness of vaccination programmes. He is co-author of more than 120 scientific articles in peer reviewed journals. He has co-authored a chapter in the textbook Vaccines 6th Edition by Plotkin S., Orenstein W., and Offit P.
Rosan Meyer
Imperial College, London
UK
Dr. Rosan Meyer
Paediatric Allergy Dietitian
Rosan completed her degree in Dietetics in South Africa and specialised in paediatric nutrition in the United Kingdom. In 2004 she went on to finish her Masters in Paediatric Nutrition and in 2008, she completed her PhD at Imperial College London on Energy Expenditure in Critically Ill Children. She was the principal research dietitian at Great Ormond Street Hospital for Children until December 2015 and has continued to supervise students on topics related to paediatric critical illness at both Imperial College and Cambridge University. In addition, she has busy a paediatric dietetic practice specialising in food allergy in London.
She is currently honorary senior lecturer Imperial College London and has taken up the role of visiting professor at KU Leuven, Belgium on the new MSc program on Deglutology. In addition she is the Chair of both the specialist Food Allergy Specialist Group of the British Dietetic Association and the European Section of the International Network for Diet and Nutrition in Allergy.
Angelo Claudio Molinari
IRCCS Istituto Giannina Gaslini
Italy
Angelo Claudio Molinari, MD is a Consultant Hematologist at the Hematology, Oncology, and Stem Cells Transplantation Program of Giannina Gaslini Children’s Hospital in Genova, Italy. He is responsible for the Thrombosis and Hemostasis Unit and Hemophilia Comprehensive Care Center, dealing with children and adults, and contractor Professor at the University of Genova. He spent all his career in studying hemorrhagic and thrombotic diseases. Dr. Molinari is involved in researches on thrombosis and stroke in children. He is member of ASH, ISTH,WFH and Italian Society for Thrombosis and Hemostasis, and actively participate to the Italian Association of Hemophilia Centers as steering committee member. Dr Molinari promoted the establishment of the Italian Registry for Pediatric Thrombosis and authored 85 full papers on hematological topics and three book chapters.
Petronella Mourad-Baars
The Netherlands
Christian Munk
Danish Cancer Society Research Center
Denmark
Christian Munk has been doing HPV research for the past 15 years with a focus on epidemiological studies on the natural history of HPV infection and HPV disease. He has been involved in cohort studies in women, which have been followed up for 15-20 years. Furthermore, he has done studies on men (soldiers) and various registry studies on HPV-associated cancers and their precursor lesions. Finally, he has participated in studies evaluating the long-term effectiveness and safety of HPV vaccination.
Affiliation: Unit of Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, DENMARK
Title/Position: Senior researcher, MD., Ph.D.
Arnold Munnich
Necker-Enfants Malades Hospital
France
Sharon Nachman
Stony Brook University School of Medicine
USA
Dr. Sharon Nachman is a clinician scientist with over 20 years of NIH funding (U mechanism from the IMPAACT network) dedicated to developing clinical trials in children and adolescents. She completed her pediatrics training at Schneider Children’s Hospital, her Pediatric Infectious Disease fellowship at Lincoln Hospital in the South Bronx, and her training as a Physician Scientist at Rockefeller University, all in NYC. Currently the Associate Dean for Research and a Professor of Pediatrics at SUNY Stony Brook, she has been involved in the development of over 25 clinical trials, including 10 as protocol chair and 8 as vice chair. All studies have enrolled, analyzed and were published, and have changed the way we assess, treat or evaluate HIV infected and exposed children worldwide. As part of her HIV related studies, she has also developed studies evaluating new and older drugs and vaccines in TB infected or at risk children. She currently serves as the PI and chair of the IMPAACT Network.
Shimon Reif
Hadassah Ein Kerem Medical Center
Israel
Prof. Shimon Reif is currently the head of the Pediatric department in Hadassah Ein Kerem Medical Center. He is a graduate of Technion Medical School, and did his Residency at Tel Aviv Medical Center followed by 3 years of fellowship in Pediatric Gastroenterology in Children’s Hospital Buffalo NY. During this period he initiated his research in liver fibrosis focusing on modulation of ECM expression during development. After his return to Israel he became head of Pediatric GI and later head of the department of Pediatrics at the Tel Aviv Medical Center. Professor Reif spent a very successful sabbatical at David Brenner lab where he promoted his research by investigating signal transduction pathway of HSCs proliferation. In the last years his research is dedicated to the anti-fibrotic mechanism of vitamin D. In addition he is the president of the Israeli pediatric GI association and associate editor of JPGN. He has more than 100 peer review publication in prestige journals.
Mattia Rizzi
Centre Hospitalier Universitaire Vaudois
Switzerland
Dr. Mattia Rizzi is staff physician in Pediatric Oncology/Haematology at the University Hospital CHUV in Lausanne, Switzerland. He graduated from the medical school at the University of Bern in 2002, and was awarded in 2007 a PhD in Tumor Biology in the Faculty of Medicine, University of Bern, Switzerland. He completed a residency in Pediatrics at the University Children’s Hospitals in Bern and Zurich in 2010 and was a clinical/research fellow in Pediatric Hematology/Oncology at the University Children’s Hospital in Zurich (2009-2011) and in Thrombosis/Hemostasis at the Division of Pediatric Hematology/Oncology at the Hospital for Sick Children in Toronto (2011-2014). His research focuses on Thrombosis in children, with a particular interest in arterial thrombosis. He has authored several publications in the field of pediatrics, as well as book chapters in pediatric hematology textbooks.
Pablo Rojo
University Hospital 12 October
Spain
Dr. Pablo Rojo
Degree/Certification:
2003 – Pediatric Specialist, HOSPITAL UNIVERSITARIO 12 DE OCTUBRE
2006 – PhD, Universidad Complutense de Madrid, Spain
1997 – MD, Universidad Complutense de Madrid, Spain
Current and previous positions including academic appointments:
2006 – Current – Associate Professor, HOSPITAL UNIVERSITARIO 12 DE OCTUBRE
2006 – Current – Associate Physician, Universidad Complutense de Madrid, Spain
2003 – 2006 – Associate Physician, Universidad Complutense de Madrid, Spain
MAIN CLINICAL TRIALS:
· BREATHER: PENTA 16 Study: Short-cycle therapy (5 days on/2 days off) in young
people with chronic HIV-infection. Ongoing.
· KONCERT: PENTA 18 Study: A Kaletra ONCE daily randomized trial of the
pharmacokinetics, safety and efficacy of twice-daily versus once-daily lopinavir/ritonavir
tablets as part of combination antiretroviral therapy in HIV-1 infected children.
· TICCH: PENTA 11 Study: Treatment interruption in children with chronic HIV-infection.
· PENPACT 1: A phase II/III randomized, open-label study of combination antiretroviral
regimens and treatment-switching strategies in HIV-1-infected antiretrivral naïve children >
30 days and < 18 years of age. · An Open-label, multicenter, multiple-dose pharmacokinetic, safety and efficacy trial of Maraviroc in combination with optimized background therapy for the treatment of ARVexperienced CCR-5 tropic HIV-1 infected children 2-18 years of age.
MAIN RECENT PUBLICATIONS:
Sainz T, Diaz L, Navarro ML, Rojo P, Blázquez D, Ramos JT, de José MI, Álvarez-Fuente M,
Serrano-Villar S, Mellado MJ, Muñoz-Fernández MA; Madrid Cohort of HIV-infected children
and adolescents, integrating the Pediatric branch of the National AIDS Research Network of
Spain (CORISPE). Cardiovascular biomarkers in vertically HIV-infected children without
metabolic abnormalities. Atherosclerosis. 2014 Apr;233(2):410-4.
Sainz T, Álvarez-Fuente M, Navarro ML, Díaz L, Rojo P, Blázquez D, de José MI, Ramos JT,
Serrano-Villar S, Martínez J, Medrano C, Muñoz-Fernández MÁ, Mellado MJ; Madrid Cohort of
HIV-infected children and adolescents integrated in the Pediatric branch of the Spanish
National AIDS Network (CoRISPE). Subclinical atherosclerosis and markers of immune
activation in HIV-infected children and adolescents: the CaroVIH Study. J Acquir Immune Defic
Syndr. 2014 Jan 1;65(1):42-9.
Barrios López M, Gómez González C, Orellana MÁ, Chaves F, Rojo P. Staphylococcus aureus
abscesses: methicillin-resistance or Panton-Valentine leukocidin presence? Arch Dis Child.
2013 Aug;98(8):608-10.
Marcel Romanos
University Hospital of Würzburg
Germany
Peter Sullivan
University of Oxford
UK
Prof. Peter Sullivan is currently Associate Professor in Paediatric Gastroenterology and Fellow of Magdalen College at the University of Oxford. He is an honorary consultant and contributes to the tertiary referral service for paediatric gastroenterology and nutrition in the Oxford region.
He trained in Manchester, Cambridge and London and has worked in India, The Gambia and Hong Kong whereat the Chinese University of Hong Kong he introduced Paediatric Gastroenterology as a sub-specialty.
Peter Sullivan was the first David Baum Fellow of the Royal College of Paediatrics and Child Health with responsibility for the international affairs of the college (2000-2006) and also past-President of the Commonwealth Association of Paediatric Gastroenterology and Nutrition. He is currently Director of Medical Education at the Oxford University Hospitals Trust and Associate Dean of the Medical Sciences Division of Oxford University with responsibility for postgraduate clinical medical training.
Ole Jakob Storebø
University of Southern Denmark
Denmark
Ole Jakob Storebø is a clinical psychologist, PhD, and trained as both individual- and group psychotherapist. He is a senior researcher at Psychiatric Research Unit in Region Zealand and honorary associate professor at Department of Psychology, University of Southern Denmark. He is editor of Cochrane Development and Psychosocial Learning Problems Group as well editor-in-chief of Scandinavian Journal of Child and Adolescent Psychiatry and Psychology. He is the leader of Center for Evidence Based Psychiatry in Region Zealand- a developmetal project.
Merit Tabbers
Emma Children’s Hospital
The Netherlands
Merit Tabbers is staff member at the paediatric gastroenterology and nutrition department in the Emma Children’s Hospital/Academic Medical Center, Amsterdam. She was trained in Paediatrics at the Emma Children’s Hospital in Amsterdam. Subsequently, she worked as a fellow at the paediatric gastroenterology and nutrition department in the Emma Children’s Hospital /Academic Medical Center. In 2011, her thesis concerned evidence-based guideline development in paediatric gastroenterology. Since then, she has been involved in different international and national guideline developments. The focus of her current clinical and research work is evidence-based guideline development, functional gastrointestinal disorders and home parenteral nutrition
Kjel Tullus
Great Ormond Street Hospital for Children
UK
Dr Tullus is a consultant Paediatric Nephrologist at Great Ormond Street Hospital for Children in London. He graduated at the Karolinska Institute, Stockholm and got his medical training in Stockholm, Sweden. He worked as a Paediatrician and Paediatric Nephrologist in Sweden, close to thirty years. He has worked in London since 2002.
His main clinical interests are inflammatory diseases like lupus and renal vasculitis, hypertension and UTI. He has tutored 5 PhD students and written more than 250 scientific papers and reviews and they have been cited more than 4300 times.
Johannes van den Anker
George Washington University
USA/Switzerland
Prof. Johannes van den Anker received his MD and PhD from the Erasmus University in Rotterdam, the Netherlands. Since 2002 he has been the Vice Chair of Pediatrics for Experimental Therapeutics and the Evan and Jones Chair in Pediatric Clinical Pharmacology at Children’s National Medical Center in Washington, and Professor of Pediatrics, Integrative Systems Biology, Pharmacology & Physiology at George Washington University School of Medicine and Health Sciences. His expertise is in developmental, neonatal and paediatric pharmacology.
He has major awards from the National Institute of Health (NIH) and leads one of only four NICHD-funded Research Centers Specialized in Pediatric Developmental Pharmacology. He has published over 300 peer reviewed papers and is member of the Editorial Board of several clinical pharmacology journals.
In 2014 he was appointed as Eckenstein-Geigy Professor of Paediatric Pharmacology at the University of Basel in Switzerland.
He is currently member of the Committee on Drugs of the American Academy of Pediatrics, President-elect of the American College of Clinical Pharmacology, and President-elect of the European Society for Developmental, Perinatal and Paediatric Pharmacology.
Heleen Van Ommen
Emma Children’s Hospital AMC
The Netherlands
Dr. Heleen Van Ommen is staff member at the Department of Pediatric Hematology in the Emma Children’s Hospital AMC, Amsterdam, the Netherlands. She received her medical education at University of Leiden. She completed a residency in pediatrics and a fellowship in pediatric hematology and oncology in the Emma Children’s Hospital AMC, Amsterdam.
She is an expert in the field of pediatric thrombosis. She received her PhD in 2002 for her thesis “Pediatric venous thromboembolic disease: epidemiology, risk factors and outcome”. Her research projects have been focused on thrombosis in children, especially children with catheters and children with malignancies. She is founder and chair of the Dutch Working group Pediatric Thrombosis and Stroke. At the moment she is co-chair of the Pediatric/Neonatal Hemostasis and Thrombosis Scientific Subcommittee of the International Society on Thrombosis and Haemostasis (ISTH).
Sascha Verbruggen
Sophia Children’s Hospital
The Netherlands
Dr Sascha Verbruggen, MD, PhD
Pediatric Intensivist, Department of Pediatric Intensive Care, Erasmus Medical Centre, Sophia Children’s Hospital, Rotterdam, The Netherlands.
Dr. Sascha Verbruggen works as attending staff in the Department of Pediatric Intensive Care, ErasmusMC – Sophia Children’s Hospital, Rotterdam, The Netherlands. He is a clinician-scientist focusing on nutrition and metabolism in critical illness, with a special interest on the long-term consequences for critically ill children. Clinically he is responsible for the (neonatal) surgical intensive care unit and is a member of the neonatal and pediatric Extra Corporeal Membrane Oxygenation (ECMO) team.
In July 2007, following his pediatric specialization at Erasmus MC – Sophia children’s hospital, Dr Verbruggen started his research training in nutrition and metabolism at the Children Nutrition Research Center (CNRC), Houston, Texas, USA (supervisors Leticia Castillo and Jorge Coss-Bu). In September 2008 he began his pediatric clinical work in the Pediatric ICU of the Erasmus MC – Sophia children’s hospital, while continuing his research in the field of nutrition & metabolism in critically ill children, which led to his PhD “Protein, Energy, and their Interaction in Critically Ill Children” in December 2010.
Together with Dr. KFM Joosten, he has established a nutrition and metabolic research unit, with ongoing research regarding nutrition and metabolism in critically ill children at the Erasmus MC – Sophia Children’s Hospital. Dr. Sascha Verbruggen is member of the nutrition and metabolism group of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC). He has published widely in his area of expertise.
He was the Principle Investigator (Rotterdam) of the multicenter study ‘Paediatric Early versus Late Parenteral Nutrition in Critical illness – PEPaNIC’, in collaboration with Prof van den Berghe, KU Leuven, Belgium, of which the results were published in the New England Journal of Medicine in 2016. Currently he is involved as principle investigator (Rotterdam) of the PEPaNIC long term follow-up study. This follow-up study not only focusses on the long term consequences of parenteral nutrition in the critically ill child and the mechanistic principles potentially responsible for the short and long term outcome, but also on the health-economic consequences of malnutrition and our interventions in the PICU.
Alexander Von Gontard
Saarland University Hospital
Germany
Prof. Dr. Alexander von Gontard is head of the the Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany and holds the chair for child and adolescent psychiatry at Saarland University. He has trained in genetics, pediatrics, child and adolescent psychiatry and psychotherapy. He has researched and published on enuresis, urinary and fecal incontinence and associated problems in children.
Arine Vlieger
St Antonius Hospital
The Netherlands
Dr. Arine Vlieger was trained as pediatrician in Utrecht, the Netherlands. After her registration as a pediatrician in 1998, she started her fellowship in pediatric immunology/ rheumatology in Utrecht, and it was there that she got interested in the body-mind connection. She was then trained in pediatric hypnotherapy in the United States. Since June 2001, she is working as a general pediatrician in the St. Antonius Hospital in Nieuwegein, the Netherlands, with a special interest in functional gastrointestinal disorders and the influence of thoughts and emotions on diseases. She finished her PhD in 2009 on “Complementary therapies in pediatric gastroenterology”. She is currently head of the department and is researcher in the field of functional gastrointestinald disorders.
Elke Wuehl
University of Heidelberg
Germany
Elke Wühl, MD, is Professor of Pediatrics and consultant pediatric nephrologist at the Center of Pediatrics and Adolescent Medicine, University of Heidelberg, Germany. She is certified pediatric nephrologist and hypertension specialist (DHL).
Her special interest is in childhood hypertension and co-morbid complications of chronic kidney disease and she is involved in numerous clinical intervention trials in the pediatric chronic kidney disease population.
She has published more than 100 articles and book chapters.
Francesco Zulian
University of Padua
Italy
Prof. Francesco Zulian graduated from Medical School in Padua Italy, specialized in Pediatric and Adult Rheumatology and since 1992 he is the Chief of the Pediatric Rheumatology Unit in Padua. From 2001-2009 he acted as Chairman of the Juvenile Scleroderma Working Group of PRES. He has been involved, as organizer and chair, of the 2001 and 2004 International Workshops on Juvenile Scleroderma Syndromes, where the Classification Criteria for Systemic Sclerosis and Localized Scleroderma in childhood were defined.
Prof. Zulian’s main research interests are in Scleroderma syndromes, Juvenile Idiopathic Arthritis (JIA) and JIA-related chronic uveitis. He has over 130 publications in International peer-reviewed Journals.